Actor Eric Dane, best known for his roles as Dr. Mark Sloan on Grey’s Anatomy and Cal Jacobs on Euphoria, passed away at the age of 53 on February 19, his family confirmed. Dane had been battling amyotrophic lateral sclerosis (ALS) since his 2025 diagnosis. In a heartfelt statement, his loved ones said he spent his final days with family and friends and became a passionate advocate for ALS awareness and research.

Eric Dane’s family issues statement

Dane was diagnosed with amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, in 2025.