Israeli strikes across Gaza killed at least 59 people, including women and children, hospital officials said on Wednesday, as Israel prepares to ramp up its campaign against Hamas in a devastating war now entering its 20th month.

The strikes included one attack on Tuesday night on a school sheltering hundreds of displaced Palestinians, which killed 27 people, officials from the Al-Aqsa Hospital said, including nine women and three children. It was the fifth time since the war began that the school in central Gaza has been struck. An early morning strike on another school turned shelter in Gaza City killed 16 people, according to officials at Al-Ahli Hospital, while strikes on targets in other areas killed at least 16 others.